What are AMPs ?
Antimicrobial peptides (AMPs) are host defense molecules universal in the innate immune systems of both invertebrates and vertebrates. Because these ancient molecules remain potent after millions of years, they are regarded as important templates for developing a new generation of antimicrobials to combat antibiotic resistant superbugs and cancer.
The antimicrobial peptide database (APD, http://aps.unmc.edu/AP/) is an original database initially online in 2003. The APD2 (2009 version) has been regularly updated and further expanded into the APD3. This database currently focuses on natural antimicrobial peptides (AMPs) with defined sequence and activity. It includes a total of 2619 AMPs with 261 bacteriocins from bacteria, 4 AMPs from archaea, 7 from protists, 13 from fungi, 321 from plants and 1972 animal host defense peptides. The APD3 contains 2169 antibacterial, 172 antiviral, 105 anti-