Founded in 1997, Genosphere Biotechnologies now enjoys thousands of literature Materials & Methods citations worldwide and contributes to just as many original Research & Development projects.  Find out more about some of these projects, several of which are destined to be a landmark in their field.

(I) Pharmacological profiling of a novel modulator of the α7 nicotinic receptor: Blockade of a toxic acetylcholinesterase-derived peptide increased in Alzheimer brains.

 Garcia-Ratés, S.  et al. (2016).  Neuropharmacology 105, pp.487-499.

(2) AMP-activated protein kinase upregulates MAP kinase interacting serine/threonine kinase 1a-dependent phosphorylation of eukaryotic translation initiation factor 4E.  

 Zhu, X. et al.  (2016).  Journal of Biological Chemistry, 291(33), pp.17020-17027.

(3) Helicobacter pylori exploits human CEACAMs via HopQ for adherence and translocation of CagA.  

 Königer, V. et al.  (2016).  Nature Microbiology, 2, p.16188.

(4) Interferon gamma peptidomimetic targeted to interstitial myofibroblasts attenuates renal fibrosis after unilateral ureteral obstruction in mice.

 Poosti, F. et al. (2016).  Oncotarget, 7(34), pp.54240-54252.

(5) Identification of a novel cell death-inducing domain reveals that fungal amyloid-controlled programmed cell death is related to necroptosis.

 Daskalov, A. et al. (2016).  Proceedings of the National Academy of Sciences 113, 2720-272

… und viele andere mehr.

Genosphere Biotechnologies

Peptidsynthesen für Ihre Forschung seit 1997