Peptidmodifikationen - (fast) so vielfältig wie die Natur.

Wir bieten aktuell die folgenden Peptidmodifikationen an:  

Labels, fluorophore, FRET

7-Amino-4-methylcoumarin, C-terminal, [amc]  

Benzyloxycarbonyl, [cbz]  

Biotin, N-terminal [biot]  

Biotin-Lys, C-terminal, internal, [K-biot]  

Dabcyl, N-terminal, [dabcyl]  

Dabcyl-Lys, C-terminal, internal, [K-dabcyl]  

Dansyl, N-terminal [dans]  

Dansyl-Ethylenediamine, C-terminal, [ed-dansyl]  

Dansyl-Lys, C-terminal, internal, [K-dansyl]  

Dinitrophenyl-Diaminopropionic acid, N-terminal, [dap-dnp]  

Dinitrophenyl-Ethylenediamine, C-terminal, [ed-dnp]  

Dinitrophenyl-Lys, N-terminal, internal, [K-dnp]  

EDANS, C-terminal [edans]  

EDANS-Glu, N-terminal, internal, [E-edans]  

Fluorescein, N-terminal, [fl]  

Fluorescein-Lys, C-terminal, internal, [K-fl]  

Methoxycoumarin acetic acid, N-terminal, [mca]  

Methoxycoumarin acetic acid-Lys, C-terminal, internal, [K-mca]  

p-Nitroaniline, C-terminal, [pNA]  

Tetramethylrhodamine, N-terminal, [tmr]  

Tetramethylrhodamine-Lys, C-terminal, internal, [K-tmr]  


N-terminal fatty acids conjugation

Myristic acid, [myr]  

Palmitic acid, [palm]  

Stearic acid, [stea]  

Oleic acid, [ole]  

Linoleic acid, [lin]  


Protein carrier conjugation

KLH, BSA, OVA  


Cyclization

Disulfide bridge (s)  

Head to tail lactam  

Internal lactam, lactone  

Thiolactone  


Spacers, linkers

C2, C4, C6, C8, C10, C12 methylene spacers  

Polyethylene glycol (PEG, PEG2, PEG3...)  

N-terminal modification

Acetyl, formyl, [ac], [for]  

Aminooxyacetyl, [aoa]  

Azide, [N3]  

Pyroglutamate, [pyr]  

S-acetylthioacetate, [sata]  

Succinyl, [suc]  


C-terminal modification

Amide, [NH2]  

Alkylester, [COOMe], [COOEt]  

Cysteamide, [cya]  

Ethylenediamine, [ed]  

Hydroxysucinimide ester, [Osu]  

N-methylamide, [NHMe]  


Non-standard residues

Aminoisobutyric acid, [aib]  

Beta aspartic acid, [beta D]  

Beta homo amino acids, [beta homo-aa]  

Beta-alanine, [beta A]  

Citrulin, [cit]  

Cyclohexylalanine, [cha]  

D amino-acids, [d-aa]  

Dihydroxyphenylalanine, [dopa]  

Epsilon lysine, [epsilon K]  

Fluoro-, chloro-, bromo phenylalanine, [x-F]  

Fluoro-, chloro-, bromo tyrosine, [x-Y]  

Gamma glutamic acid [gamma E]  

Heavy isotope (13C, 15N) labeled amino-acids  

Hydroxyproline, [hyp]  

Methyl-, acetyl-lysine [meK], [acK]  

N-methyl amino-acids, [N-Me-aa]  

Norleucine, [nle]  

Pencillinamine, [pen]  

Phosphorylation [pS], [pT], [pY]  


  

                 

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