Allgemeines Anwendungsbeispiel.

FOR RESEARCH USE ONLY.


Desmopressin Acetate for Injection

Vials:1ml:xxμg / 1ml:xxμg


Indications and Usage:


A. Shortening or normalisation of prolonged bleeding time prior to an invasive therapeutic or diagnostic operation, or for therapeutic control of bleeding in patients with prolonged bleeding time as a consequence of congenital or substance-induced thrombocyte dysfunction, uremia, cirrhosis of the liver or in patients with prolonged bleeding time of unknown etiology.


B. For the therapeutic control of bleeding and bleeding prophylaxis in connection with minor surgical procedures in patients with mild haemophilia A and von Willebrand’s disease who respond positively to a test dose. In exceptional cases, even moderate forms of the disease can be treated. MINIRIN must not be used in patients with von Willebrand’s disease type IIB.


C. Treatment of central diabetes insipidus and for establishing renal concentration capacity testing.


Therapeutic indications:


Central diabetes insipidus

If the intranasal presentation is not available (do not use for children) , desmopressin acetate for injection can be used. Dose adjusted according to patient’s urine volume and urine osmotic pressure.

Normal dose by intramuscular injection: Adults x-x µg, 1-2 times/day, for children above the age of 1 year, x-x µg, 1-2 times/day is recommended. For children below the age of 1 year, 0.x µg is recommended. Drip according to patient’s urine volume and electrolyte.


C. Kidney urine concentration test

Normal dose by intramuscular or subcutaneous injection: Adults 4µg (1ml), for children above the age of 1 year, x-x µg is recommended. For children below the age of 1 year, 0.x µg is recommended. For children it is recommended to use primarily the intranasal presentation. After administration of desmopressin acetate for injection any urine collected within one hour is discarded. During the next 8 hours 2 portions of urine are collected for measurement of osmolality. Fluid restriction should be observed.




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